Towa Higurashi learns about an incident that took place decades ago involving a half demon named Inuyasha and a priestess named Kagome.

Half-demon twins Towa and Setsuna are separated from each other when a mysterious tunnel sends Towa into the future, where she is found and raised by Kagome Higurashi’s brother Sota.

In the present day, a demon emerges through the Sacred Tree at Higurashi Shrine with Setsuna, Towa’s twin, and the bounty hunter Moroha in tow. Towa, Setsuna, and Moroha struggle to battle the demon, whose powers have been strengthened with two Rainbow Pearls, but seeing Setsuna in trouble awakens Towa’s latent demon powers.

Towa decides to return to the feudal era to help Setsuna regain her memories. The trio enter the corridor leading to the feudal era, but within it awaits the spirit of a certain priestess.

Safely back in the feudal era, Moroha heads to the corpse dealer to claim her bounty. Meanwhile, Towa and Setsuna take on a request to slay Jakotsumaru, a boy who has been extracting bones from humans and beasts in order to revive his father, the demon beast Tokotsu.

Travelers are going missing one after another. Towa, Setsuna, and Moroha head to the northern mountains to crack the case, but instead they find a village completely overrun by ghost cats!

On her way to search for the Dream Butterfly, Towa meets a strange young man named Riku. Towa offers him an apple, and in thanks, Riku presents her with the genuine Kikujumonji sword.

The owl demon Yotsume flees the deputy shogun’s estate to the lair of Kyuki, a member of the Four Perils. Kyuki lends Yotsume a Rainbow Pearl to help him unleash his Dream Gazing spell upon the Half-Demon Princesses, who are hot on his trail.

Moroha accepts a job to slay Konton, a member of the Four Perils said to have defeated Meioju, a demon beast with the ultimate armored shell.

The Half-Demon Princesses are tasked with slaying Kinka and Ginka, conjoined twins of the Ka Demon Tribe whose battles for dominance have been wreaking havoc everywhere.

Something wicked lurks in the Man-Eating Pond, devouring any human, beast or bird that comes near. On their way to slay the creature, Towa and Setsuna meet Hikomaru and Chiyo, siblings who lost their parents to the pond.

Nikosen was a sage before evil consumed his soul and transformed him into a demon. Konton orders him to kill the Half-Demon Princesses. Nikosen’s ambush catches Towa at a bad time, when her demon powers are fading and she is slowing turning into a human.

When a demon begins to devour virtuous monks and Shinto priests in the region, Hisui is assigned to guard his father, Miroku, who has been undergoing harsh training for the past two years.

Towa and Setsuna set off to slay Homura, an evil mountain god who has abducted a beautiful maiden named Tamano. However, Homura is shocked at the sight of the twins; it turns out that he was involved in the forest fire that separated them ten years ago.

The truth behind the night that sealed the fate of Towa, Setsuna, and Moroha’s parents is finally revealed.

Moroha once had a master named Yawaragi, who was keeping a life-threatening secret. In order to resolve the secret and protect her pupil, Yawaragi made an agreement with Jyubei.

Konton devises a plan to destroy the Half-Demon Princesses. Riku offers to help him out, letting the girls know that the man-eating demon Totetsu has reappeared. The three are lured into a ravine by Totetsu and fall right into Konton’s trap.

Konton learns of the origins of the Rainbow Pearl and the connection between Kirinmaru and the Dream Butterfly. He summons an ogre to attack the Half-Demon Princesses.

The deputy shogun’s daughter Aiya offers to employ the demon slayers if they win in a battle against the bounty hunters.

Setsuna opens up to Towa about the hidden village for half-demons where she was raised for most of her childhood.

On the night of the new moon, Towa learns more about her human mother, Rin. Riku pays Towa a visit to tell her about the ones who took care of him. Unfortunately, he’s not the only one planning to drop by.

Zero removes the seal that Miroku placed on Setsuna to suppress her demon powers, awakening the latent demon blood within. Towa and Moroha struggle to subdue the transformed Setsuna.

Setsuna and Towa hire Moroha to help slay Zero. The trio successfully track Zero down, but Riku is there to protect her. They stand on the battlefield where the Great Dog Demon took his last breath.

Zero cuts ties with her younger brother and flees the scene. Towa, Setsuna, and Moroha are left to confront Kirinmaru, but in the face of overwhelming power, they must pay a great price.